Insider Activity Highlights a Quiet RSU Vesting Cycle The most recent filing from Precision BioSciences’ CEO, Michael Amoroso, shows a classic vesting event: three sets of Restricted Stock Units (RSUs) each vested on January 20, 2026, totaling 115,298 shares. The transaction is a “buy” under the SEC’s classification, but the shares are not purchased at market price; they simply become part of the CEO’s holdings once the vesting conditions are met. This pattern mirrors the company’s long‑standing RSU grant program, which releases equity in three annual installments. While the event itself is routine, the sheer volume—over 115,000 shares—highlights the scale of the compensation structure and the amount of equity tied to the company’s leadership.

Implications for Investors Amid a Volatile Share Price Precision’s stock is currently trading around $4.01, a steep decline from the 52‑week high of $8.82. The negative price‑to‑earnings ratio of –0.49 signals earnings that are essentially zero or negative, a common trait among biotech firms still in the development phase. The RSU vesting, therefore, does not represent a liquidity event for insiders but rather a reinforcement of long‑term alignment with shareholders. Investors may interpret the continued vesting of significant equity as a vote of confidence from the CEO that the company’s long‑term prospects justify the risk. However, the recent sell‑to‑cover of 34,799 shares on January 22—executed under a Rule 10b5‑1 plan to cover tax liabilities—indicates a modest level of short‑term cash flow needs, a normal practice for high‑earning executives.

What the CEO’s Transaction Pattern Tells Us Amoroso’s historical filing record shows a steady stream of RSU grants and periodic sales of common stock, typically in the range of 3,000–9,000 shares per transaction. He has also sold RSUs outright, often in batches matching the vesting schedule. This disciplined approach suggests he prefers to lock in value through equity rather than liquidate it, a strategy that aligns his incentives with the company’s performance. The most recent sale of 3,409 shares on November 3, 2025, was at a price of $6.49, indicating a willingness to realize gains when the market is favorable, but the bulk of his holdings remain vested or locked in.

Company‑Wide Insider Momentum Beyond the CEO, other top executives—such as CFO Kelly John Alexander, General Counsel Dario Scimeca, and Chief Research Officer J. Jefferson—have collectively executed more than 30 transactions in the last 30 days. Their activity is heavily skewed toward buying common stock, with several large purchases (up to 26,575 shares) occurring on January 20, 2026. These cumulative purchases, totaling over 200,000 shares across the leadership team, signal a collective confidence in the company’s pipeline, despite the current share price volatility.

Investor Takeaway For investors watching Precision BioSciences, the recent insider activity offers a mixed but largely positive signal. The CEO’s large RSU vesting underlines a strong equity‑centric compensation philosophy, while the pattern of incremental stock purchases by other executives reinforces their belief in the company’s long‑term prospects. The lack of significant sell‑offs, aside from tax‑cover transactions, suggests insiders are not rushing to liquidate holdings amid the current market dip. In a biotech space where valuations are tightly coupled to development milestones, this insider steadiness may provide a reassuring backdrop for those considering a longer‑term stake in the company.

DateOwnerTransaction TypeSharesPrice per ShareSecurity
2026-01-20Amoroso Michael (President and CEO)Buy8,888.000.00Common Stock
2026-01-20Amoroso Michael (President and CEO)Buy37,069.000.00Common Stock
2026-01-20Amoroso Michael (President and CEO)Buy69,421.000.00Common Stock
2026-01-22Amoroso Michael (President and CEO)Sell34,799.004.17Common Stock
2026-01-20Amoroso Michael (President and CEO)Sell8,888.00N/ARestricted Stock Units
2026-01-20Amoroso Michael (President and CEO)Sell37,069.00N/ARestricted Stock Units
2026-01-20Amoroso Michael (President and CEO)Sell69,421.00N/ARestricted Stock Units
2026-01-20Kelly John Alexander (Chief Financial Officer)Buy3,888.000.00Common Stock
2026-01-20Kelly John Alexander (Chief Financial Officer)Buy13,900.000.00Common Stock
2026-01-20Kelly John Alexander (Chief Financial Officer)Buy26,575.000.00Common Stock
2026-01-21Kelly John Alexander (Chief Financial Officer)Sell15,213.004.03Common Stock
2026-01-20Kelly John Alexander (Chief Financial Officer)Sell3,888.00N/ARestricted Stock Units
2026-01-20Kelly John Alexander (Chief Financial Officer)Sell13,900.00N/ARestricted Stock Units
2026-01-20Kelly John Alexander (Chief Financial Officer)Sell26,575.00N/ARestricted Stock Units
2026-01-20Scimeca Dario (General Counsel and Secretary)Buy1,978.00N/ACommon Stock
2026-01-20Scimeca Dario (General Counsel and Secretary)Buy8,425.00N/ACommon Stock
2026-01-20Scimeca Dario (General Counsel and Secretary)Buy14,908.00N/ACommon Stock
2026-01-21Scimeca Dario (General Counsel and Secretary)Sell8,854.004.03Common Stock
2026-01-20Scimeca Dario (General Counsel and Secretary)Sell1,978.00N/ARestricted Stock Units
2026-01-20Scimeca Dario (General Counsel and Secretary)Sell8,425.00N/ARestricted Stock Units
2026-01-20Scimeca Dario (General Counsel and Secretary)Sell14,908.00N/ARestricted Stock Units
2026-01-20SMITH J. JEFFERSON (Chief Research Officer)Buy2,500.000.00Common Stock
2026-01-20SMITH J. JEFFERSON (Chief Research Officer)Buy10,447.000.00Common Stock
2026-01-21SMITH J. JEFFERSON (Chief Research Officer)Buy16,219.000.00Common Stock
2026-01-21SMITH J. JEFFERSON (Chief Research Officer)Sell10,200.004.03Common Stock
N/ASMITH J. JEFFERSON (Chief Research Officer)Holding7,931.00N/ACommon Stock
2026-01-20SMITH J. JEFFERSON (Chief Research Officer)Sell2,500.00N/ARestricted Stock Units
2026-01-20SMITH J. JEFFERSON (Chief Research Officer)Sell10,447.00N/ARestricted Stock Units
2026-01-20SMITH J. JEFFERSON (Chief Research Officer)Sell16,219.00N/ARestricted Stock Units