Insider Activity Spotlight: Vertex’s Executive Trades and Market Signals

Current Transaction and Market Context

On February 17, 2026, EVP of Corporate Operations and Finance Charles Wagner bought 7,365 shares of Vertex at zero cost—an award of restricted stock units set to vest in 2027—while simultaneously selling 2,294 shares at $483.75 each. The sale occurred when the stock hovered near $470, a level that has been the most recent trading high in the last year. The buy‑sell pair reflects a common pattern among senior executives: capturing value from vesting awards while monetizing a portion of their equity stake. For investors, the transaction signals that Wagner is comfortable with Vertex’s valuation, yet is also maintaining liquidity through a modest sale. The market, which has seen a modest 0.91% uptick that day, remains largely indifferent, with a neutral sentiment score of 0 and a social‑media buzz at 539%, indicating that the move did not provoke a strong narrative.

Implications for Investors and the Company’s Outlook

Vertex’s insider activity is steady but not aggressive. Across the last quarter, senior executives have executed a mix of buys and sells, often balancing short‑term cash needs with long‑term commitment. The fact that Wagner and his peers are still adding to their positions—despite frequent sales—suggests confidence in the company’s pipeline, especially in cystic fibrosis and emerging indications such as sickle cell disease. From a valuation perspective, the stock’s 52‑week high of $519.68 remains out of reach, but the current price of $470 is well within the range that historically has led to quarterly earnings growth. For shareholders, a cautious approach is warranted: the recent sales provide liquidity without eroding long‑term upside, while the continued purchases hint that insiders see sustainable value creation ahead.

Charles Wagner: A Profile of Executive Trading Behavior

Wagner’s trade history over the past six months illustrates a disciplined approach. He has sold an average of 4,000–5,000 shares each month, often at prices above the market average, and has purchased roughly the same number of shares in restricted‑stock units or through deferred‑stock‑unit awards. His net exposure has hovered around 50,000 shares, a position that balances influence with the risk of being viewed as a “dividend‑seeker.” Compared to peers such as CEO Reshma Kewalramani, who has maintained a larger stake, Wagner’s activity is modestly more aggressive in selling, likely reflecting his dual role in finance and operations. Historically, Wagner’s trades have not coincided with major corporate announcements, suggesting he is not reacting to immediate news but rather following a long‑term investment thesis.

What This Means for the Future

If Vertex continues its current trajectory—expanding its pipeline and securing regulatory approvals—the insider activity pattern is likely to persist. Executives will likely continue to sell a portion of their equity to fund personal liquidity needs while simultaneously committing through vesting awards to align interests with shareholders. For investors, this behavior can be interpreted as a sign of confidence: insiders are not shying away from the stock, nor are they dumping en masse. The moderate volatility in the share price, combined with steady insider participation, points to a company that is managing growth expectations while maintaining executive engagement. In the coming quarters, watch for any large sales that might precede earnings releases or regulatory milestones, as those could signal shifts in executive sentiment.

DateOwnerTransaction TypeSharesPrice per ShareSecurity
2026-02-17WAGNER CHARLES F JR (EVP, CO & FO)Buy7,365.00N/ACommon Stock
2026-02-17WAGNER CHARLES F JR (EVP, CO & FO)Sell2,294.00483.75Common Stock
2026-02-17Tatsis Ourania (EVP, Chief Reg. & Quality Off.)Buy5,789.00N/ACommon Stock
2026-02-17Tatsis Ourania (EVP, Chief Reg. & Quality Off.)Sell2,294.00483.75Common Stock
2026-02-17Tatsis Ourania (EVP, Chief Reg. & Quality Off.)Sell609.00489.46Common Stock
2026-02-18Tatsis Ourania (EVP, Chief Reg. & Quality Off.)Sell368.00473.68Common Stock
2026-02-17Sachdev Amit (EVP Chief Patient & Ext Af Off)Buy5,789.00N/ACommon Stock
2026-02-17Sachdev Amit (EVP Chief Patient & Ext Af Off)Sell2,140.00483.75Common Stock
N/ASachdev Amit (EVP Chief Patient & Ext Af Off)Holding882.00N/ACommon Stock
N/ASachdev Amit (EVP Chief Patient & Ext Af Off)Holding9,301.00N/ACommon Stock
2026-02-17McKechnie Duncan (EVP, Chief Commercial Officer)Buy4,962.00N/ACommon Stock
2026-02-17McKechnie Duncan (EVP, Chief Commercial Officer)Sell1,148.00483.75Common Stock
2026-02-17LEIDEN JEFFREY M (Executive Chairman)Buy8,269.00N/ACommon Stock
2026-02-18LEIDEN JEFFREY M (Executive Chairman)Sell2,964.00483.75Common Stock
N/ALEIDEN JEFFREY M (Executive Chairman)Holding440.00N/ACommon Stock
2026-02-17Kewalramani Reshma (CEO & President)Buy16,326.00N/ACommon Stock
2026-02-17Kewalramani Reshma (CEO & President)Sell6,554.00483.75Common Stock
2026-02-17Bunnage Mark E. (EVP, Chief Scientific Officer)Buy2,584.00N/ACommon Stock
2026-02-17Bunnage Mark E. (EVP, Chief Scientific Officer)Sell1,110.00483.75Common Stock
2026-02-17Bunnage Mark E. (EVP, Chief Scientific Officer)Sell2,437.00489.46Common Stock
2026-02-18Bunnage Mark E. (EVP, Chief Scientific Officer)Sell1,182.00473.68Common Stock
2026-02-17Bozic Carmen (EVP and CMO)Buy5,375.00N/ACommon Stock
2026-02-17Bozic Carmen (EVP and CMO)Sell1,912.00483.75Common Stock
2026-02-17Biller Jonathan (EVP and Chief Legal Officer)Buy4,135.00N/ACommon Stock
2026-02-17Biller Jonathan (EVP and Chief Legal Officer)Sell1,505.00483.75Common Stock
2026-02-17Biller Jonathan (EVP and Chief Legal Officer)Sell2,476.00489.46Common Stock
2026-02-18Biller Jonathan (EVP and Chief Legal Officer)Sell1,244.00473.68Common Stock
2026-02-17Atkinson Edward Morrow III (EVP, Chief Technical Ops. Off.)Buy4,962.00N/ACommon Stock
2026-02-17Atkinson Edward Morrow III (EVP, Chief Technical Ops. Off.)Sell1,530.00483.75Common Stock
2026-02-17Atkinson Edward Morrow III (EVP, Chief Technical Ops. Off.)Sell2,031.00489.46Common Stock
2026-02-18Atkinson Edward Morrow III (EVP, Chief Technical Ops. Off.)Sell817.00473.68Common Stock
2026-02-17Ambrose Kristen (SVP & Chief Accounting Officer)Buy1,809.00N/ACommon Stock
2026-02-17Ambrose Kristen (SVP & Chief Accounting Officer)Sell598.00483.75Common Stock
2026-02-17Ambrose Kristen (SVP & Chief Accounting Officer)Sell1,557.00489.46Common Stock
2026-02-18Ambrose Kristen (SVP & Chief Accounting Officer)Sell638.00473.68Common Stock